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Article

Causal Interplay Between Inflammatory Cytokines and Lipid Metabolites in Serous Ovarian Carcinoma: Insights From a Genetic Association Study.

Journal of clinical laboratory analysis - 1 Jun 2026

Yang Chong-Ze, Qin Lan-Hui, Huang Cheng-Can, Huang Xiao-Li, Yang Ying-Xia, Lan Wei, Fan Miao

Abstract excerpt

BACKGROUND: The causal roles and interactions of inflammatory cytokines and metabolic reprogramming in serous ovarian carcinoma (SOC) remain unclear. This study explored their relationships using Mendelian randomization (MR). METHODS: In this two-sample MR analysis, GWAS data of inflammatory cytokines and blood metabolites were used as exposures, and SOC from the FinnGen consortium served as the outcome. Inverse...

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Share to Cystadenocarcinoma, Serous
Share to Cytokines

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to CXCL1 gene

Share to Genome-Wide Association Study

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Share to Mendelian Randomization Analysis

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Share to Polymorphism, Single Nucleotide

Source

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Identifiers

PMID: 42104642
DOI: 10.1002/jcla.70250
PMCID: PMC13327467

Genes

CSF1
CXCL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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