Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Inflammatory factors and risk of lung adenocarcinoma: a Mendelian randomization study mediated by blood metabolites.

Frontiers in endocrinology - 1 Jan 2024

Ding Zheng, Chen Juan, Li Bohan, Ji Xinyu

Abstract excerpt

Background: Lung adenocarcinoma (LUAD) is the most common type of lung cancer, and its pathogenesis remains not fully elucidated. Inflammation and metabolic dysregulation are considered to play crucial roles in LUAD development, but their causal relationships and specific mechanisms remain unclear. Methods: This study employed a two-sample Mendelian randomization (MR) approach to systematically evaluate the...

Topics

Join the communities discussing this publication.

Inflammation
Interleukin-17
Adenocarcinoma of Lung
Genome-Wide Association Study
Lung Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mendelian Randomization Analysis

Polymorphism, Single Nucleotide

Source

Open in PubMed Open full text

Identifiers

PMID: 39257908
DOI: 10.3389/fendo.2024.1446863
PMCID: PMC11384989

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Inflammatory factors and risk of lung adenocarcinoma: a Mendelian randomization study mediated by blood metabolites.PMID 39257908Read ↗

Exploring Metabolites as Therapeutic Targets in Lung Cancer: Insights from Mendelian RandomizationSemantic proximity Read ↗

Causal Relationships Between Plasma Metabolites, Inflammatory Factors, and Oral Cancer Risk: A Comprehensive Mendelian Randomization Study With Mediation Analysis.Semantic proximity Read ↗

Chronic Obstructive Pulmonary Disease Influence on Lung Cancer Risk Through Blood Metabolite Mediation: A Two-Sample Mendelian Randomisation and Mediation Analysis.Semantic proximity Read ↗

Prognostic biomarkers for lung adenocarcinoma based on Mendelian randomization analysisSemantic proximity Read ↗

Multi-omics Reveals Metabolic-Inflammatory Drivers of Lung Cancer: An Integrated Mendelian Randomization and Machine Learning StudySemantic proximity Read ↗

Causal relationships of inflammatory cytokines and serum metabolites with colorectal carcinoma: A Mendelian randomization study.Semantic proximity Read ↗

Systematic Mendelian randomization using the human plasma proteome to identify therapeutic targets for lung adenocarcinomaSemantic proximity Read ↗

Causal Interplay Between Inflammatory Cytokines and Lipid Metabolites in Serous Ovarian Carcinoma: Insights From a Genetic Association Study.Semantic proximity Read ↗

Mendelian randomization study on the association of circulating ketone bodies with lung cancer and respiratory diseases.Semantic proximity Read ↗

Causal effects of circulating inflammatory proteins on COPD: A Mendelian randomization study.Semantic proximity Read ↗

Causal association of circulating cytokines with the risk of lung cancer: a Mendelian randomization studySemantic proximity Read ↗

Causal relationships between immune cell phenotypes and lung adenocarcinoma: A bidirectional two-sample Mendelian randomization study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.