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Evaluating the association between lipidome and female reproductive diseases through comprehensive Mendelian randomization analyses

19 Jan 2025

Abstract excerpt

This study aimed to assess the causal relationship between lipidome and female reproductive diseases (FRDs) using an advanced series of Mendelian randomization (MR) methods. This study utilized genome-wide association study (GWAS) summary statistics encompassing 179 lipidomes and six prevalent FRDs, namely polycystic ovary syndrome (PCOS), endometriosis, uterine fibroid, female infertility, uterine endometrial...

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PMID: 39828767
DOI: 10.1038/s41598-025-86794-2

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