Article
Beyond association: Mediation roles of lipidomics and cytokine in PCOS uncovered by cross-disciplinary genomics.
Prostaglandins & other lipid mediators - 1 Jul 2026
Lang Tingyu, Yang Yongxiu
Abstract excerpt
BACKGROUND AND AIMS: Polycystic ovary syndrome (PCOS) is a metabolic disorder that significantly impacts female fertility. Lipids and inflammation are key factors in the pathogenesis and progression of PCOS. This study aims to elucidate the complex causal relationships involving 179 lipids, 91 inflammatory markers, and PCOS using robust Mendelian Randomization (MR) methods based on Genome-Wide Association Studies...
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