Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genome-wide studies of heart failure and endophenotypes: lessons learned and future directions.

Cardiovascular research - 15 Jul 2018

van der Ende Maaike Yldau, Said Mir Abdullah, van Veldhuisen Dirk Jan, Verweij Niek, van der Harst Pim

Abstract excerpt

Heart failure (HF) is a complex clinical syndrome resulting from structural or functional impairments of ventricular filling or ejection of blood. HF has a poor prognosis and the burden to society remains tremendous. The unfulfilled expectation is that expanding our knowledge of the genetic architecture of HF will help to quickly advance the quality of risk assessment, diagnoses, and treatment. To date,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Diffusion of Innovation
Share to Forecasting

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genetic Markers

Share to Genome-Wide Association Study

Share to Heart Failure

Share to History, 20th Century

Share to History, 21st Century

Share to Prognosis

Source

Identifiers

PMID: 29912321
DOI: 10.1093/cvr/cvy083

Genes

MYBPC3
NPPB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genome-wide studies of heart failure and endophenotypes: lessons learned and future directions.PMID 29912321Read ↗

Mapping the aetiological foundations of the heart failure spectrum using human geneticsSemantic proximity Read ↗

Genome-wide association study meta-analysis provides insights into the etiology of heart failure and its subtypes.Semantic proximity Read ↗

Genetic Biomarkers in Heart Failure: From Gene Panels to Polygenic Risk Scores.Semantic proximity Read ↗

Phenotypic Refinement of Heart Failure in a National Biobank Facilitates Genetic DiscoverySemantic proximity Read ↗

The Genetic Factors Influencing Cardiomyopathies and Heart Failure across the Allele Frequency Spectrum.Semantic proximity Read ↗

Genetics of common forms of heart failure: challenges and potential solutions.Semantic proximity Read ↗

Heart failure: advanced development in genetics and epigenetics.Semantic proximity Read ↗

Genome-wide association and multi-omic analyses reveal new mechanisms for Heart FailureSemantic proximity Read ↗

Pharmacogenomics of the Natriuretic Peptide System in Heart Failure.Semantic proximity Read ↗

Determined to Fail--the Role of Genetic Mechanisms in Heart Failure.Semantic proximity Read ↗

Genome-wide analysis of heart failure yields insights into disease heterogeneity and enables prognostic prediction in the Japanese populationSemantic proximity Read ↗

Common- and rare-variant genetic architecture of heart failure across the allele frequency spectrumSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.