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Article

The Genetics of Iron Metabolism on Biochemical and Hematological Phenotypes of Heart Failure.

International journal of molecular sciences - 23 Apr 2026

Barbosa Mário, Aguiar Laura, Matias Ana, Ferreira Joana, Caldeira João, Melício Ana, Faustino Paula, Falcão Luiz Menezes, Bicho Manuel, Inácio Ângela

Abstract excerpt

Heart failure (HF) is frequently associated with iron deficiency and anemia, negatively impacting patient outcomes. This study aimed to investigate the contribution of genetic variation in iron metabolism-related genes to biochemical and hematological phenotypes in HF. An HF population of 182 patients with functional iron deficiency (ID) and anemia was stratified by sex and heart failure subtype, including HF...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 42123363
DOI: 10.3390/ijms27093778
PMCID: PMC13163690

Genes

HFE
SLC40A1
TMPRSS6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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