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Article

No evidence for an association between the -36A>C phospholamban gene polymorphism and a worse prognosis in heart failure.

BMC cardiovascular disorders - 28 Jul 2009

Santos Diogo G B, Medeiros Alessandra, Brum Patrícia C, Mill José G, Mansur Alfredo J, Krieger José E, Pereira Alexandre C

Abstract excerpt

BACKGROUND: In Brazil, heart failure leads to approximately 25,000 deaths per year. Abnormal calcium handling is a hallmark of heart failure and changes in genes encoding for proteins involved in the re-uptake of calcium might harbor mutations leading to inherited cardiomyopathies. Phospholamban (PLN) plays a prime role in cardiac contractility and relaxation and mutations in the gene encoding PLN have been...

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Identifiers

PMID: 19638213
DOI: 10.1186/1471-2261-9-33
PMCID: PMC2734742

Genes

PLN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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No evidence for an association between the -36A>C phospholamban gene polymorphism and a worse prognosis in heart failure.PMID 19638213Read ↗

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Molecular Characterization of Phospholamban and Reninangiotensin System Genes Mutations and Clinical Epidemiology in Human CardiomyopathySemantic proximity Read ↗

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