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Article

Genomic profiling and therapeutic targets of Thai melanoma revealed by next-generation sequencing.

Scientific reports - 3 May 2026

Kamdee Kornyok, Pithukpakorn Manop, Sitthinamsuwan Panitta, Paringkarn Teerapat, Thumrongtharadol Janista, Achariyapota Vuthinun, Taweepraditpol Sitthichoke, Chairatchaneeboon Manasmon

Abstract excerpt

Genetic alterations represent key therapeutic targets in melanoma, but genomic profiles differ across ethnic groups and remain poorly defined in Thai patients. We characterized the somatic landscape of 33 melanoma samples (13 cutaneous, 13 acral, 7 mucosal) using the 501-gene OCA-Plus panel with next-generation sequencing, integrating clinical and genomic features. The somatic landscape revealed BRAF as the most...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 42071048
DOI: 10.1038/s41598-026-51731-4
PMCID: PMC13332027

Genes

BRAF
KIT
MYC
NRAS

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 25 Oct 2026.

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