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Single-cell lineage tracing unveils sex differences in VSMCs derived from the cardiac neural crest and second heart field.

Vascular pharmacology - 1 Jun 2026

Wang Yanzhi, Luo Cheng, Wang Songmao, Li Li, Fu Kailong, Lyu Qing Rex

Abstract excerpt

Stanford type A thoracic aortic aneurysm and dissection (TAAD) affects the ascending aorta and aortic arch and can cause sudden death due to rupture. Epidemiological studies have shown that TAAD occurs more frequently in men than women. Vascular smooth muscle cells (VSMCs) are one of the major cell types in the vascular wall and play a critical role in the pathogenesis of TAAD. Recent studies have highlighted the...

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PMID: 42069076
DOI: 10.1016/j.vph.2026.107611

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SHF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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