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Article

Impact of dose-adjusted tacrolimus exposure phenotype on outcomes in kidney transplantation: a large-scale multicenter cohort study.

Frontiers in immunology - 1 Jan 2026

Lim Donghyun, Kim Sangwan, Han Ahram, Ahn Jayeon, Kim Young Hoon, Huh Kyu Ha, Park Jae Berm, Park Sun Cheol, Ha Jongwon, Min Sangil

Abstract excerpt

Introduction: Dose-adjusted tacrolimus exposure phenotype, expressed as the trough concentration-to-dose ratio (C0/Dose), may influence post-transplant outcomes, but supporting evidence remains limited. Methods: We evaluated the association between tacrolimus exposure phenotype and short- and long-term allograft and patient outcomes in a multicenter retrospective cohort study using clinical data warehouse records...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 42064065
DOI: 10.3389/fimmu.2026.1811657
PMCID: PMC13124564

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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