Article
Clinical phenomapping and outcomes after heart transplantation.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation - 1 Aug 2018
Bakir Maral, Jackson Nicholas J, Han Simon X, Bui Alex, Chang Eleanor, Liem David A, Ardehali Abbas, Ardehali Reza, Baas Arnold S, Press Marcella Calfon, Cruz Daniel, Deng Mario C, DePasquale Eugene C, Fonarow Gregg C, Khuu Tam, Kwon Murray H, Kubak Bernard M, Nsair Ali, Phung Jennifer L, Reed Elaine F, Schaenman Joanna M, Shemin Richard J, Zhang Qiuheng J, Tseng Chi-Hong, Cadeiras Martin
Abstract excerpt
BACKGROUND: Survival after heart transplantation (HTx) is limited by complications related to alloreactivity, immune suppression, and adverse effects of pharmacologic therapies. We hypothesize that time-dependent phenomapping of clinical and molecular data sets is a valuable approach to clinical assessments and guiding medical management to improve outcomes. METHODS: We analyzed clinical, therapeutic, biomarker,...
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