Article
Blood pressure response index trajectories identify distinct hemodynamic phenotypes and predict mortality in septic shock: a two-database retrospective cohort study.
Critical care (London, England) - 29 Apr 2026
Shen Yongshi, Zhang Wei, Lin Kangni, Zheng Peng, Liu Xinwei, Weng Jinsen, Ye Yong
Abstract excerpt
BACKGROUND: Vasopressor responsiveness in septic shock is typically assessed using static metrics that cannot capture temporal hemodynamic evolution. The Blood Pressure Response Index (BPRI = mean arterial pressure / Vasoactive-Inotropic Score) integrates hemodynamic response and treatment intensity into a single metric, but its longitudinal trajectory patterns remain unexplored. METHODS: We applied latent class...
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