Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identifying a Refractory Shock Phenotype in Pediatric Sepsis Using a Vasoactive-Adjusted Shock Index.

Shock (Augusta, Ga.) - 1 Aug 2026

Lee Cheolmin Matthew, Atreya Mihir R, Bennett Tellen D, Farris Reid Wd, Faustino E Vincent S, Geva Alon, Rogerson Colin M, Shah Sareen, Weiss Scott, Sanchez-Pinto L Nelson

Abstract excerpt

OBJECTIVES: This study aimed to: 1) develop a cardiovascular index that includes hemodynamic status and adjusts for vasoactive medication use; 2) identify pediatric patients with refractory septic shock (RSS) using early trends of the adjusted index, and 3) assess the heterogeneity of treatment effect (HTE) to common adjuvant therapies in RSS versus non-RSS patients. METHODS: Children with sepsis across 13 US...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to Child

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Child, Preschool

Share to Hemodynamics

Share to Infant

Share to Sepsis

Share to Shock, Septic

Share to Vasoconstrictor Agents

Source

Identifiers

PMID: 42241407
DOI: 10.1097/SHK.0000000000002886

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identifying a Refractory Shock Phenotype in Pediatric Sepsis Using a Vasoactive-Adjusted Shock Index.PMID 42241407Read ↗

Derivation, validation, and clinical relevance of a pediatric sepsis phenotype with persistent hypoxemia and shockSemantic proximity Read ↗

Derivation, Validation, and Clinical Relevance of a Pediatric Sepsis Phenotype With Persistent Hypoxemia, Encephalopathy, and Shock.Semantic proximity Read ↗

EMERGENCE OF A TECHNOLOGY-DEPENDENT PHENOTYPE OF PEDIATRIC SEPSIS IN A LARGE CHILDREN'S HOSPITAL.Semantic proximity Read ↗

Generalized Prediction of Hemodynamic Shock in Intensive Care UnitsSemantic proximity Read ↗

Derivation of four computable 24-hour pediatric sepsis phenotypes to facilitate personalized enrollment in early precise anti-inflammatory clinical trialsSemantic proximity Read ↗

Machine learning derivation of four computable 24-h pediatric sepsis phenotypes to facilitate enrollment in early personalized anti-inflammatory clinical trials.Semantic proximity Read ↗

Pediatric Sepsis Biomarker Risk Model-II: Redefining the Pediatric Sepsis Biomarker Risk Model With Septic Shock PhenotypeSemantic proximity Read ↗

Pediatric Sepsis Diagnosis, Management, and Sub-phenotypes.Semantic proximity Read ↗

Identification and transcriptomic assessment of latent profile pediatric septic shock phenotypes.Semantic proximity Read ↗

Diastolic/systolic blood pressure ratio for predicting febrile children with sepsis and progress to septic shock in the Emergency DepartmentSemantic proximity Read ↗

Pediatric Sepsis Phenotypes and Outcome: 5-Year Retrospective Cohort Study in a Single Center in India (2017-2022).Semantic proximity Read ↗

External validation and biomarker assessment of a high-risk, data-driven pediatric sepsis phenotype characterized by persistent hypoxemia, encephalopathy, and shock.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.