Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Hereditary pancreatic cancer: A proposal for surveillance from the Italian Association for the Study of the Pancreas (AISP).

Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver - 1 Aug 2026

Carrara Silvia, Archibugi Livia, Terrin Maria, Secchettin Erica, De Luca Raffaele, Paiella Salvatore

Abstract excerpt

Genetic and familial susceptibility accounts for 10% of pancreatic ductal adenocarcinoma (PDAC) cases and represents a small but relevant subgroup in which early detection may meaningfully affect outcomes. Pathogenic germline variants (PGVs) in susceptibility genes, such as BRCA2/ATM/CDKN2A/STK11/PALB2/TP53, as well as mismatch repair genes, confer a substantially higher lifetime risk, while families fulfilling...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma
Share to Carcinoma, Pancreatic Ductal

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Early Detection of Cancer

Share to Genetic Predisposition to Disease

Share to Pancreatic Neoplasms

Share to Population Surveillance

Share to Registries

Source

Identifiers

PMID: 42036279
DOI: 10.1016/j.dld.2026.04.007

Genes

ATM
BRCA2
CAPS
CDKN2A
PALB2
STK11
TP53

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 9 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Hereditary pancreatic cancer: A proposal for surveillance from the Italian Association for the Study of the Pancreas (AISP).PMID 42036279Read ↗

The Italian registry of families at risk for pancreatic cancer (IRFARPC): implementation and evolution of a national program for pancreatic cancer surveillance in high-risk individuals.Semantic proximity Read ↗

Management of patients with increased risk for familial pancreatic cancer: updated recommendations from the International Cancer of the Pancreas Screening (CAPS) Consortium.Semantic proximity Read ↗

Italian registry of families at risk of pancreatic cancer: AISP Familial Pancreatic Cancer Study Group.Semantic proximity Read ↗

Hereditary Pancreatic Cancer: Genetic Risk, Surveillance Strategies, and Therapeutic Implications.Semantic proximity Read ↗

Familial pancreatic cancer--status quo.Semantic proximity Read ↗

The Spanish Familial Pancreatic Cancer Registry (PANGENFAM): a decade follow-up of individuals at high-risk for pancreatic cancer.Semantic proximity Read ↗

Familial pancreatic cancer.Semantic proximity Read ↗

The benefit of pancreatic cancer surveillance in carriers of germline BRCA1/2 pathogenic variants.Semantic proximity Read ↗

The German National Case Collection for Familial Pancreatic Cancer (FaPaCa)Semantic proximity Read ↗

Familial pancreatic cancer: Concept, management and issues.Semantic proximity Read ↗

Identification of high-risk germline variants for the development of pancreatic cancer: Common characteristics and potential guidance to screening guidelines.Semantic proximity Read ↗

The role of germline BRCA1 & BRCA2 mutations in familial pancreatic cancer: A systematic review and meta-analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.