Article
The benefit of pancreatic cancer surveillance in carriers of germline BRCA1/2 pathogenic variants.
Cancer - 1 Jan 2024
Laish Ido, Schechter Menachem, Dancour Alain, Lieberman Sari, Levi Zohar, Goldberg Yael, Kedar Inbal, Hasnis Erez, Half Elizabeth, Levi Gili Reznick, Katz Lior, Vainer Elez D, Genzel Dor, Aharoni Maya, Chen-Shtoyerman Rakefet, Abu-Freha Naim, Raitses-Gurevich Maria, Golan Talia, Bernstein-Molho Rinat, Ben Yehoyada Merav, Gluck Nathan, Rosner Guy
Abstract excerpt
BACKGROUND: Surveillance of high-risk individuals for pancreatic ductal adenocarcinoma (PDAC) is recommended. This study aimed to determine the prevalence and outcomes of PDAC and its precursor lesions in BRCA1/2 pathogenic variants (PVs) carriers undergoing pancreatic surveillance. METHODS: A retrospective multicenter cohort study of pancreatic surveillance outcomes in Israeli BRCA1/2 carriers preferably with a...
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