Article
Familial pancreatic cancer: Concept, management and issues.
World journal of gastroenterology - 14 Feb 2017
Matsubayashi Hiroyuki, Takaori Kyoichi, Morizane Chigusa, Maguchi Hiroyuki, Mizuma Masamichi, Takahashi Hideaki, Wada Keita, Hosoi Hiroko, Yachida Shinichi, Suzuki Masami, Usui Risa, Furukawa Toru, Furuse Junji, Sato Takamitsu, Ueno Makoto, Kiyozumi Yoshimi, Hijioka Susumu, Mizuno Nobumasa, Terashima Takeshi, Mizumoto Masaki, Kodama Yuzo, Torishima Masako, Kawaguchi Takahisa, Ashida Reiko, Kitano Masayuki, Hanada Keiji, Furukawa Masayuki, Kawabe Ken, Majima Yoshiyuki, Shimosegawa Toru
Abstract excerpt
Familial pancreatic cancer (FPC) is broadly defined as two first-degree-relatives with pancreatic cancer (PC) and accounts for 4%-10% of PC. Several genetic syndromes, including Peutz-Jeghers syndrome, hereditary pancreatitis, hereditary breast-ovarian cancer syndrome (HBOC), Lynch syndrome, and familial adenomatous polyposis (FAP), also have increased risks of PC, but the narrowest definition of FPC excludes...
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