Article
CNDP1 (CTG)5 allele and cardiovascular events in high-risk patients: LURIC study results.
Scientific reports - 21 Apr 2026
Hettler Steffen A, Moissl Angela, Delgado Graciela E, Skladny Heyko, März Winfried, Krämer Bernhard K, Yard Benito A, Kleber Marcus E
Abstract excerpt
Homozygous carriers of the CNDP1 (CTG)5 allele with diabetes mellitus are believed to have a lower risk of developing diabetic kidney disease compared to individuals carrying alleles with higher numbers of this CTG repeat. However, recent studies claimed that homozygosity for the (CTG)5 allele increases the risk of disease progression towards end-stage renal disease and even cardiovascular mortality, at least in...
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