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Article

The fortunate amelioration of Costus speciosus on phenotypes of letrozole-induced polycystic ovary syndrome in female rats.

Brazilian journal of biology = Revista brasleira de biologia - 1 Jan 2026

Elmazoudy R, Alqosaibi A, Alnamshan M, Al-Dhuayan I, AlAhmady N F, Alsayyah A, Alhawaj H A

Abstract excerpt

Endocrine disruption, infertility, anovulation, impaired cyclicity, and ovarian damage are complications of polycystic ovary syndrome (PCOS). Herein, we explore the potential role of Costus speciosus extract in letrozole-induced polycystic ovary syndrome in female rats. For PCOS induction, letrozole 1.0 mg/kg body weight was given orally for 90 days. Four groups of female rats were randomly assigned. Group 1, the...

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PMID: 41983838
DOI: 10.1590/1519-6984.298520

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