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Transcriptomic analysis of theca cells in a PCOS rat model: insights into follicular development

21 Jun 2025

Abstract excerpt

BACKGROUND: This study aimed to analyze differentially expressed genes in theca cells of polycystic ovary syndrome (PCOS) rats using transcriptomic sequencing. Bioinformatics analysis and PCR validation were performed to identify genes involved in follicular development regulation in PCOS. METHODS: Twenty 6-week-old female SD rats with regular estrous cycles were divided into two groups (PCOS and control, n = 10...

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Share to Growth Hormone and Insulin-like Growth Factors
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PMID: 40544268
DOI: 10.1186/s13048-025-01663-w

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