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Article

Orosomucoid 2 improves reproductive phenotypes in a mouse model of PCOS induced by letrozole under high-fat diet conditions.

Molecular human reproduction - 7 Jan 2026

Xu Qiuyu, Qiu Shuwen, Wang Li, Liu Yali, Lu Yan, Wu Ling, Zhang Jie

Abstract excerpt

Polycystic ovary syndrome (PCOS) is the most common reproductive endocrine disorder among women of reproductive age. It is characterized by excess androgens, anovulation, and polycystic ovarian morphology, and is often accompanied by obesity, insulin resistance, and glucose metabolism abnormalities. Although PCOS is a complex disease with diverse and uncertain etiologies, metabolic dysfunction and adipose tissue...

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Identifiers

PMID: 41645455
DOI: 10.1093/molehr/gaag005

Genes

ORM2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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