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Article

Rare variant optimized GWAS with functional validation identifies causal architecture of kidney function in East Asian population.

Scientific reports - 14 Apr 2026

Jang Jiyun, Choi Jaeyong, Moon Sungji, Kim Jeong Mi, Kim Jong-Il, Im Sun-Wha

Abstract excerpt

Chronic kidney disease is a growing burden, yet the genetic architecture of kidney function requires further investigation. We performed a genome-wide association study of estimated glomerular filtration rate in 72,298 Korean individuals using a population-specific Korean Biobank Array and genetic imputation with a population matching imputation panel enabling high-resolution variant detection. We identified 30...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 41981041
DOI: 10.1038/s41598-026-47877-w
PMCID: PMC13237097

Genes

TBX2
TBX5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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