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Article

Functional network analysis in hepatolithiasis: identifying novel therapeutic targets through whole-exome sequencing.

PeerJ - 1 Jan 2026

Tang Dan, Gu Xuanyu, Liu Dan, Yang Jiali, Zhao Lijin

Abstract excerpt

Background: Hepatolithiasis (HL) is a prevalent condition in hepatobiliary surgery, often complicated by hepatatrophia. This study aimed to identify gene mutations in HL specimens with hepatatrophia and construct a mutation landscape using whole-exome sequencing (WES). Methods: Genetic variants and copy number variations (CNVs) were compared between HL (n = 10) and normal control (NC, n = 10) specimens,...

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Share to DNA Copy Number Variations
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 41978884
DOI: 10.7717/peerj.21059
PMCID: PMC13070319

Genes

FAAH
TMEM150B
ATRN
TNIP1
WNT8B
RAX
TF
C1RL
HINFP
NFYA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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