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Article

Analyzing soluble and lung smooth muscle laminin isoform expression in guinea pigs exhibiting various allergic response phenotypes.

Frontiers in immunology - 1 Jan 2026

Pacheco-Alba Ivonne, Flores-Flores Angélica, Bazán-Perkins Blanca

Abstract excerpt

Introduction: Ovalbumin (OVA) sensitization in guinea pigs induces a distinct phenotype of allergic responses, among which the asthma model is the most extensively studied. A functionally opposite phenotype is the non-responder (NR), which, despite exhibiting high levels of OVA-specific IgE and IgG1, does not develop airway obstruction or hyperresponsiveness after chronic antigen challenge. This phenotype differs...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41953025
DOI: 10.3389/fimmu.2026.1774996
PMCID: PMC13053283

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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