Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Unraveling the inflammatory bridge: genomic evidence identifies TNFRSF9 as a potential biomarker linking Sjögren's syndrome to total risk non-Hodgkin lymphoma.

Clinical rheumatology - 1 Jun 2026

Wang Hongye, Yan Helin, Yang Mifeng, Zhang Yingyi, Zhang Jia, Zhouyang Mengqian, Zhao Bo

Abstract excerpt

BACKGROUND: Patients with Sjögren's syndrome (SS) are at significantly increased risk of developing non-Hodgkin lymphoma (NHL). However, effective biomarkers to identify the subgroup of SS patients who will progress to lymphoma are currently lacking. This study aims to elucidate the causal mechanisms linking SS to NHL and to identify circulating inflammatory protein biomarkers for risk stratification. METHODS:...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers
Share to Genome-Wide Association Study

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Lymphoma, Non-Hodgkin

Share to Mendelian Randomization Analysis

Share to Polymorphism, Single Nucleotide

Share to Receptors, Tumor Necrosis Factor

Share to Risk Factors

Share to Sjogren's Syndrome

Source

Identifiers

PMID: 41952027
DOI: 10.1007/s10067-026-08092-0

Genes

TNFRSF9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 9 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Unraveling the inflammatory bridge: genomic evidence identifies TNFRSF9 as a potential biomarker linking Sjögren's syndrome to total risk non-Hodgkin lymphoma.PMID 41952027Read ↗

Inflammatory cytokines and their potential role in Sjogren’s syndrome risk: insights from a mendelian randomization studySemantic proximity Read ↗

Contribution of Genetic Factors to Sjögren's Syndrome and Sjögren's Syndrome Related Lymphomagenesis.Semantic proximity Read ↗

Exploring risk factors for autoimmune diseases complicated by non-hodgkin lymphoma through regulatory T cell immune-related traits: a Mendelian randomization study.Semantic proximity Read ↗

The causal role of immune cells in primary Sjögren's syndrome: A two-sample Mendelian randomization.Semantic proximity Read ↗

A comprehensive review of Sjögren's syndrome: Classification criteria, risk factors, and signaling pathwaysSemantic proximity Read ↗

Sjögren's syndrome: one year in review 2023Semantic proximity Read ↗

Causal associations of Sjögren’s syndrome with cancers: a two-sample Mendelian randomization studySemantic proximity Read ↗

Gut microbiota may influence Sjögren's syndrome risk through immune cell mediation: A Mendelian randomization analysis.Semantic proximity Read ↗

Genome-wide association study identifies Sjögren's risk loci with functional implications in immune and glandular cells.Semantic proximity Read ↗

Identification of Genetic Predisposition to Sjögren’s Syndrome by Whole Exome SequencingSemantic proximity Read ↗

Primary Sjögren's syndrome: clinical phenotypes, outcome and the development of biomarkers.Semantic proximity Read ↗

Genetics and genomics of Sjögren's syndrome: research provides clues to pathogenesis and novel therapies.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.