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Article

The causal role of immune cells in primary Sjögren's syndrome: A two-sample Mendelian randomization.

International journal of rheumatic diseases - 1 Nov 2024

Liu Yang, Kang Jie, Su Yazhen, Fan Xiuying, Ma Dan, Wu Zewen, Gong Xueyan, Zhao Junkang, Zhang Liyun

Abstract excerpt

BACKGROUND: Primary Sjögren's syndrome (pSS) is an autoimmune disease characterized by the destruction of exocrine glands primarily via T-cell-mediated B-cell over-activation and cytokine production. This leads to pronounced dryness of the mouth and eyes and can result in multi-systemic involvement affecting the kidneys, lungs, and blood. In recent years, there has been increasing attention on the role of immune...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39558620
DOI: 10.1111/1756-185X.15350

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