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Article

Asthma in Children With Melanocortin 4 Receptor (MC4R) Gene Mutation Variant: A Case Series.

Pediatric pulmonology - 1 Apr 2026

Al-Dhmour Haitham, Zahra Mahmoud Abu, Rastogi Deepa

Abstract excerpt

BACKGROUND: Melanocortin 4 receptor (MC4R) gene mutations are the most common cause of monogenic non-syndromic childhood obesity, but their relationship with asthma remains unclear. METHODS: We report four cases of children with the same MC4R gene variant who presented with asthma in the setting of obesity. RESULTS: The asthma phenotype, severity, and presentation were variable between these patients. Some but...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Receptor, Melanocortin, Type 4

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Source

Identifiers

PMID: 41944526
DOI: 10.1002/ppul.71611

Genes

MC4R

Provenance

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