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Article

Severe obstructive sleep apnea in a child with melanocortin-4 receptor deficiency.

Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine - 15 Jan 2014

Pillai Sophia, Nandalike Kiran, Kogelman Yelena, Muzumdar Radhika, Balk Sophie J, Arens Raanan

Abstract excerpt

Obstructive sleep apnea (OSA) is a highly prevalent medical condition in obese children and is associated with significant neurocognitive, cardiovascular and metabolic derangements. Monogenic forms of obesity resulting from disruption of the leptin-melanocortin pathways have become more notable in recent years and distinguish between various obese phenotypes. However, the association of such disorders with OSA is...

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Identifiers

PMID: 24426828
DOI: 10.5664/jcsm.3374
PMCID: PMC3869078

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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