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Article

Primary biliary cirrhosis and rheumatoid arthritis: a comprehensive study combining genetics and transcriptomics.

Mammalian genome : official journal of the International Mammalian Genome Society - 6 Apr 2026

Yang Mingyi, Ren Honghao, Ren Xiaodong, Wen Pengfei, Xie Jiale, Wan Xianjie, Xu Ke, Liu Lin, Hou Weikun, Yang Zhi, Xu Peng

Abstract excerpt

Observational investigations have discerned a correlation between primary biliary cirrhosis (PBC) and rheumatoid arthritis (RA). The primary objective of this study is to elucidate the disease risk correlation between them in terms of genetics, and to explore the genes and signaling pathways involved. We acquired genome-wide association studies (GWAS) summary data for PBC and RA from distinct repositories: PBC...

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Share to Arthritis, Rheumatoid
Share to Gene Expression Profiling

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome-Wide Association Study

Share to Liver Cirrhosis, Biliary

Share to Mendelian Randomization Analysis

Share to Polymorphism, Single Nucleotide

Share to Signal Transduction

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Source

Identifiers

PMID: 41942635
DOI: 10.1007/s00335-026-10224-5

Genes

MANBA
CCR6
IL12RB2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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