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Article

Resistance associated genomic variations for moderate level tigecycline resistance evolution in Acinetobacter baumannii.

World journal of microbiology & biotechnology - 4 Apr 2026

Acharya Kusumita, Biswas Shatarupa, Bhattacharyya Sayani, Ghosh Mallika, Bhattacharya Arijit

Abstract excerpt

Among the last-resort antibiotics, tigecycline is a semisynthetic drug derivative of tetracycline used in medical facilities, resulting in tigecycline-resistant Acinetobacter baumannii (TRAB) strain development. Recent reports suggested the emergence of heteroresistance, intermediate-resistance, and resistance strain development against the tigecycline of A. baumannii isolates, causing treatment failure in...

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PMID: 41933192
DOI: 10.1007/s11274-026-04908-y

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