Article
Comparative genomic analysis of rapid evolution of an extreme-drug-resistant Acinetobacter baumannii clone.
Genome biology and evolution - 1 Jan 2013
Tan Sean Yang-Yi, Chua Song Lin, Liu Yang, Høiby Niels, Andersen Leif Percival, Givskov Michael, Song Zhijun, Yang Liang
Abstract excerpt
The emergence of extreme-drug-resistant (EDR) bacterial strains in hospital and nonhospital clinical settings is a big and growing public health threat. Understanding the antibiotic resistance mechanisms at the genomic levels can facilitate the development of next-generation agents. Here, comparative genomics has been employed to analyze the rapid evolution of an EDR Acinetobacter baumannii clone from the...
Topics
- Acinetobacter Infections
- Acinetobacter baumannii
- Anti-Bacterial Agents
- Comparative Genomic Hybridization
- Cross Infection
- DNA Fingerprinting
- Drug Resistance, Bacterial
- Genome, Bacterial
- Humans
- Molecular Epidemiology