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Article

Synergistic Effects of Early Psychosocial Factors and Polygenic Risk for Smoking: a Cross-Sectional Analysis of a Sample of Older Adults in the United States.

Developmental psychobiology - 1 May 2026

Dyer Walter G, Lee Sung-Ha, Wilding Hannah, Sutara Brianna, Lee Harold H

Abstract excerpt

Genetic influence on smoking may be modified by negative early psychosocial factors (EPFs). However, few studies have examined this interaction. We hypothesized that negative EPFs will exacerbate the association between genetic risk for smoking and ever smoking. We used data on European Americans (EA) and African Americans (AA) from the Health and Retirement Study (HRS). Polygenic score for "ever smoking"...

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Identifiers

PMID: 41917796
DOI: 10.1002/dev.70152
PMCID: PMC13039236

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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