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Article

Investigating the shared genetic architecture between inflammatory bowel disease and pancreatitis: a genome-wide cross-trait analysis.

Molecular genetics and genomics : MGG - 1 Apr 2026

Qi Hang-Ming, Liu Ting-Ting, Chen Jia-Yun, Wang Ya-Hui, Mao Xiao-Tong, Wang Yuan-Chen, Jin Jing, Lin Xi, Yang Jianfeng, Zou Wen-Bin, Kang Le, Liao Zhuan

Abstract excerpt

Epidemiological studies suggested comorbidity between inflammatory bowel disease (IBD) and pancreatitis. However, little is known about their shared genetic architecture. Based on genome-wide association studies (GWAS), we utilized Mendelian randomization (MR) method to investigate the causal relationships between IBD (including ulcerative colitis (UC) and Crohn's disease (CD)) and pancreatitis (including acute...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41917235
DOI: 10.1007/s00438-026-02406-2

Genes

CP
SPINK5
TRPV6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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