Article
Characterization of patient-derived HPV16 E6 and E7 variant alleles.
Journal of virology - 21 Apr 2026
Grace Miranda, Beeravolu Harshita, Alhamshari Ahmad, Skelin Josipa, Kiessling Si-Young, Bohm Andrew, White Elizabeth A, Munger Karl
Abstract excerpt
Human papillomavirus type 16 (HPV16) is the most prevalent carcinogenic HPV type. Many HPV16 sequence variants have been described, some of which cause protein-coding mutations. However, most experiments have characterized the viral proteins encoded by the HPV16 prototype clone, and some researchers have proposed that variants identified in high-grade lesions and cancers may have higher oncogenic potential than...
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