Article

ZER1 contributes to the carcinogenic activity of high-risk HPV E7 proteins

2022-07-19

Abstract excerpt

<h4>ABSTRACT</h4> Human Papillomavirus (HPV) E7 proteins bind to host cell proteins to facilitate virus replication. Interactions between HPV E7 and host cell proteins can also drive cancer progression. We hypothesize that HPV E7-host protein interactions specific for high-risk E7 contribute to the carcinogenic activity of high-risk HPV. The cellular protein ZER1 interacts with the E7 protein from HPV16, the geno...

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Identifiers and source

Literature Corpus work: c395883f-30e7-5674-a004-ca17d07d6597
DOI: 10.1101/2022.07.18.500567

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