Article
Diagnostic Utility of Single Nucleotide Polymorphism Microarray in Evaluating Pancreaticobiliary Brushing Specimens in Conjunction with Conventional Cytology.
The Journal of molecular diagnostics : JMD - 1 Jun 2026
Alptekin Ahmet, Mondal Ashis K, Vashisht Ashutosh, Vashisht Vishakha, Singh Harmanpreet, Morera Daley, Ahluwalia Pankaj, Farmaha Jaspreet, Kavuri Sravankumar, Patel Nikhil, Velasquez Zarate Luis A, Sridhar Subbaramiah, Chandrasekar Viveksandeep T, Kolhe Ravindra
Abstract excerpt
Bile duct brushings are noninvasive samplings of cells from the biliary tract for cytologic evaluation and are useful to diagnose pancreaticobiliary malignancies. Although specificity of cytology is satisfactory, sensitivity is inherently low because of challenging or absent morphologic features. Using molecular markers by incorporating fluorescence in situ hybridization has significantly improved sensitivity and...
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