Article
Combined effects of lncRNA MIR17HG polymorphisms and lifestyle-related risk factors on the development and progression of tongue squamous cell carcinoma.
Bioscience reports - 20 May 2026
Yang Yi-Chieh, Ding Yi-Fang, Lin Chiao-Wen, Liu Yu-Fan, Ho Kuo-Hao, Chang Lun-Ching, Yang Shun-Fa, Chien Ming-Hsien
Abstract excerpt
Oral squamous cell carcinoma is the most common malignancy of the oral cavity, with tongue squamous cell carcinoma (TSCC) being particularly prevalent worldwide. Evidence suggests that the long noncoding RNA, miRNA 17-92a-1 cluster host gene (MIR17HG), plays dual roles in tumor development. However, its clinical relevance and genetic variation in TSCC remain unclear. Analysis of data from TCGA revealed that...
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