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Article

Oxidative Stress-Related Genome-Wide Mendelian Randomization Identifies Causal Genes for Coronary Artery Disease.

Cardiovascular therapeutics - 1 Jan 2026

Zhang Hongliang, Feng Jingsheng, Shi Wence, Niu Guannan, Zheng Yanqin, Zhao Zhenyan, Wang Moyang, Zhou Zheng, Li Zhe, Wu Yongjian

Abstract excerpt

Although oxidative stress (OS) links to the pathogenesis of coronary artery disease (CAD), its underlying genetic mechanisms remain unclear. Through summary data-based Mendelian randomization (SMR) and colocalization, this research seeks to assess the potential causal links between OS-related genes and CAD. Summary-level data on the methylation, expression, and protein abundance levels of OS-related genes were...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 41873862
DOI: 10.1155/cdr/4594769
PMCID: PMC13140796

Genes

CAD
SMARCA4
NAGLU

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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