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Article

Sex differences in frailty: Comparisons between humans and preclinical models.

Mechanisms of ageing and development - 1 Sept 2021

Kane Alice E, Howlett Susan E

Abstract excerpt

Frailty can be viewed as a state of physiological decline that increases susceptibility to adverse health outcomes. This loss of physiological reserve means that even small stressors can lead to disability and death in frail individuals. Frailty can be measured with various clinical tools; the two most popular are the frailty index and the frailty phenotype. Clinical studies have used these tools to show that...

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PMID: 34324923
DOI: 10.1016/j.mad.2021.111546

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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