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Article

Characterization of T-cell receptor loci and expressed repertoire reveals a capacity for robust T-cell response in Atlantic cod (Gadus morhua).

Scientific reports - 22 Mar 2026

Györkei Ádám, Johansen Finn-Eirik, Qiao Shuo-Wang

Abstract excerpt

The Atlantic cod presents a peculiar case in fish immunology, due to the loss of MHCII and CD4 genes. Despite the absent antibody response to T cell-dependent antigens, it is a prolific species. Characterization of T-cell receptor loci and the expressed repertoire is necessary to further our understanding of how the Atlantic cod can mount an effective immune response and to characterize its immune system on the...

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Gadus morhua
CD4 gene
TRA gene
TRD gene
Genetic Variation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Receptors, Antigen, T-Cell

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Open in PubMed Open full text

Identifiers

PMID: 41865102
DOI: 10.1038/s41598-026-45018-x
PMCID: PMC13149839

Genes

TRA
TRB
TRD
CD4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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