Article
Diversity, molecular characterization and expression of T cell receptor γ in a teleost fish, the sea bass (Dicentrarchus labrax, L).
PloS one - 1 Jan 2012
Buonocore Francesco, Castro Rosario, Randelli Elisa, Lefranc Marie-Paule, Six Adrien, Kuhl Heiner, Reinhardt Richard, Facchiano Angelo, Boudinot Pierre, Scapigliati Giuseppe
Abstract excerpt
Two lineages of T cells, expressing either the αβ T cell receptor (TR) or the γδ TR, exist in Gnathostomes. The latter type of T cells account for 1-10 % of T cells in blood and up to 30 % in the small intestine. They may recognize unconventional antigens (phosphorylated microbial metabolites, lipid antigens) without the need of major histocompatibility class I (MH1) or class II (MH2) presentation. In this work...
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