Article
Genetic and Transcriptomic Profiles Identify Potential Therapeutic Targets of Concurrent Follicular and Diffuse Large B-Cell Lymphoma and Transformed Follicular Lymphoma.
Hematological oncology - 1 Mar 2026
Sun Rui, Li Rui-Chi, Li Hui-Ying, Wang Nan, Xu Tian-Yuan, Tian Shuang, Fu Di, Li Chen, Zhang Fang-Yi, Feng Yan, Cheng Shu, Xu Peng-Peng, Wang Li, Zheng Zhong, Zhao Wei-Li
Abstract excerpt
Concurrent follicular and diffuse large B-cell lymphoma (FL/DLBCL) and transformed follicular lymphoma (tFL) are distinct B-cell lymphoma entities, posing challenges for understanding pathogenesis and clinical management. The clinical characteristics of 98 FL/DLBCL, 31 tFL, 403 FL1-2/3A, and 608 DLBCL patients were analyzed. DNA sequencing was performed in these cohorts, and RNA sequencing was performed on 60...
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