Article
HLA - C*03:02:02 and DPA1*01:03:01 protect against discoid rash in Thai Systemic Lupus Erythematosus patients.
Scientific reports - 18 Mar 2026
Khor Seik-Soon, Hirankarn Nattiya, Kunhapan Punna, Mahasirimongkol Surakameth, Pisitkun Prapaporn, Eu-Ahsunthornwattana Jakris, Aekplakorn Wichai, Jinawath Natini, Neelapaichit Nareemarn, Tangtanatakul Pattarin
Abstract excerpt
This study aims to characterized high-resolution HLA alleles in Thai SLE patients and investigate their clinical correlations.The 6 digits HLA allele imputation was conducted using previously published Thai genotyping array data (SLE = 892, healthy controls = 1,638), utilizing population-matched HLA sequencing data as reference (n = 381). The HLA genes (HLA-A, HLA-C, HLA-B, HLA-DRB1, HLA-DQA1, HLA-DQB1, HLA-DPA1,...
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