Article
Meta-analysis of genome-wide association study identifies FBN2 as a novel locus associated with systemic lupus erythematosus in Thai population.
Arthritis research & therapy - 8 Aug 2020
Tangtanatakul Pattarin, Thumarat Chisanu, Satproedprai Nusara, Kunhapan Punna, Chaiyasung Tassamonwan, Klinchanhom Siriwan, Wang Yong-Fei, Wei Wei, Wongshinsri Jeerapat, Chiewchengchol Direkrit, Rodsaward Pongsawat, Ngamjanyaporn Pintip, Suangtamai Thanitta, Mahasirimongkol Surakameth, Pisitkun Prapaporn, Hirankarn Nattiya
Abstract excerpt
BACKGROUND: Differences in the expression of variants across ethnic groups in the systemic lupus erythematosus (SLE) patients have been well documented. However, the genetic architecture in the Thai population has not been thoroughly examined. In this study, we carried out genome-wide association study (GWAS) in the Thai population. METHODS: Two GWAS cohorts were independently collected and genotyped: discovery...
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