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Article

Associations between polygenic risk scores for Alzheimer's disease and postoperative delirium risk.

Journal of Alzheimer's disease : JAD - 1 May 2026

Chen Yun Jin, Gaba Arlen, Yang Hui-Wen, Maher Matthew, Saxena Richa, Li Peng, Hu Kun, Gao Lei

Abstract excerpt

BackgroundPostoperative delirium (POD) affects up to a third of older surgical patients, leading to significant morbidity, mortality, and potential progression to Alzheimer's disease (AD). Polygenic risk scores (PRS) capture inherited susceptibility to complex diseases, but their relevance to POD is unclear.ObjectiveWe examined whether higher AD-PRS predict increased POD risk in patients without dementia and...

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Identifiers

PMID: 41837651
DOI: 10.1177/13872877261430955
PMCID: PMC13409415

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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