Article
Association of MMP-2 and MMP-9 Polymorphisms and the Pathogenesis of Childhood Burkitt's Lymphoma.
Pediatric blood & cancer - 1 May 2026
da Silva Elienay Ferreira, Neto Frederico Marcos Chaves Frazão de Carvalho Ramos, de Lima Elker Lene Santos, Neto Adauto Gomes Barbosa, Muniz Maria Tereza Cartaxo
Abstract excerpt
INTRODUCTION: Burkitt lymphoma (BL) is a highly aggressive and invasive non-Hodgkin lymphoma derived from germinal center B cells and represents one of the most common childhood malignancies. Matrix metalloproteinases (MMPs) play a critical role in cancer progression by remodeling the extracellular matrix and modulating the tumor microenvironment. In advanced stages, MMPs facilitate tumor invasion and metastasis...
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