Article
Association between matrix metalloproteinase 2 (MMP2) promoter polymorphisms and the susceptibility to non-Hodgkin's lymphoma in Egyptians.
Annals of hematology - 1 Aug 2014
Gouda Heba Mahmoud, Khorshied Mervat Mamdooh, El Sissy Maha Hamdi, Shaheen Iman Abdel Mohsen, Mohsen Mohsen Mokhtar Abdel
Abstract excerpt
Matrix metalloproteinases (MMPs) are zinc-dependent endopeptidases capable of extracellular matrix degradation. MMP2 is the key molecule that control invasion, tumor growth, and metastasis, and has been associated with poor prognosis in several tumors. Several epidemiological studies have focused on the associations between MMP2 promoter polymorphisms and cancer susceptibility; however, little is known about...
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