Article
Dietary one‑carbon nutrients and genetic risk in Parkinson disease: a prospective cohort study.
The journals of gerontology. Series A, Biological sciences and medical sciences - 7 Apr 2026
Tao Junliang, Wang Yongsheng, Xia Xuedan, Li Yafang, Deng Xinxin, Zhang Faqiang, Huang Jiayi, Liang Cui, He Qiangsheng, Zhu Ye, Yang Kehu, Yuan Jinqiu, Wang Di, Li Xiuxia
Abstract excerpt
BACKGROUND: Several studies have investigated the effects of dietary one-carbon metabolism (OCM) nutrients, such as methionine, folate, vitamin B6, and vitamin B12, on Parkinson disease (PD). However, current evidence remains insufficient to definitively establish a link between OCM intake, PD incidence, and genetic risk. METHODS: Among 202 171 individuals aged 37 to 73 in the UK Biobank, we assessed dietary OCM...
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