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Article

Associations among dietary 1-carbon metabolism nutrients, genetic risk, and Alzheimer disease: a prospective cohort study.

The American journal of clinical nutrition - 1 Nov 2024

Wang Yongsheng, Mi Ningning, Liao Kun, Li Yan, Sun Yuxuan, Xie Peng, Hu Linmin, Wu Siqing, Liang Zixin, He Qiangsheng, Li Zijun, Ma Mina, Yang Kehu, Yuan Jinqiu, Xia Bin, Li Xiuxia

Abstract excerpt

BACKGROUND: The associations between 1-carbon metabolism (OCM) nutrients (methionine, folate, vitamin B-6, and vitamin B-12) and Alzheimer disease (AD) remains inconclusive. OBJECTIVES: This study aimed to investigate the association of dietary OCM nutrients with subsequent risk of AD and further assess whether participants with high genetic risk for AD might benefit from dietary OCM nutrients. METHODS: We...

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PMID: 39216592
DOI: 10.1016/j.ajcnut.2024.08.027

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OCM

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