Article
Association of a Healthy Lifestyle with Risk of Parkinson's Disease and Genetic Predisposition.
Neuroepidemiology - 1 Jan 2026
Jiang Qirui, Lin Junyu, Wei Qianqian, Li Chunyu, Ou Ruwei, Zhang Lingyu, Hou Yanbing, Yang Tianmi, Xiao Yi, Wang Shichan, Liu Jiyong, Zheng Xiaoting, Shang Huifang
Abstract excerpt
INTRODUCTION: Parkinson's disease (PD) is the second most common neurodegenerative disease with largely unknown etiology. Evaluating the association between a healthy lifestyle with PD and genetic risk is necessary. METHODS: The study included 438,241 participants from the UK Biobank, with lifestyle information collected via baseline questionnaires. Polygenic risk scores (PRS) were divided into quartiles. The...
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