Article
Clinicopathological characteristics and prognostic outcomes in consecutive Japanese patients with high microsatellite-instability colorectal cancer: real-world data from universal screening.
BMC gastroenterology - 13 Mar 2026
Inoue Akira, Nishizawa Yujiro, Hashimoto Masahiro, Ozato Yuki, Morimoto Yoshihiro, Furukawa Kenta, Hirota Masashi, Miyazaki Yasuhiro, Tomokuni Akira, Motoori Masaaki, Fujitani Kazumasa
Abstract excerpt
BACKGROUND: High microsatellite instability (MSI-H) is an established prognostic marker in various cancers, including colorectal, gastric, and endometrial cancers. However, comprehensive real-world data from universal screening in Asian populations remain limited. We aimed to evaluate the clinicopathological and prognostic impact of MSI-H status in Japanese patients with colorectal cancer (CRC). METHODS: This...
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